Mycophenolic acid

Description: 
Therapeutic drug monitoring for patients on immunosuppressant drugs. Analysis by tandem mass spectrometry. Assay run every day including weekends and bank holidays.

For same-day analysis, samples must be received by the laboratory by 14:00 on weekdays and 10:30 at weekends/bank holidays. Please give the laboratory prior notice if you are sending samples at the weekend/bank holiday (Mon-Fri 9:00-5:00 – 07738 897225 / 020 7188 9652). On weekends/bank holidays, the Scientist running the assay can be contacted on 07718 195096 (core hours 11:00 – 14:00).

Please send a request form with adequate patient information and clear contact details to enable efficient communication of results out of hours.
Clinical details: 
Mycophenolic acid (MPA) is an immunosuppressive agent which exerts it's effect by inhibiting the growth of B and T cells of the immune system. It is important to monitor the blood concentration of MPA as at toxic concentrations patients are susceptible to a number of side effects including leukopenia and anaemia. At sub-therapeutic dosage patients may experience transplant rejection. MPA is increasingly used as a steroid-sparing treatment in other autoimmune mediated disorders, for example psoriasis.
Reference range: 

Please contact the laboratory to discuss

Synonyms or keywords: 
Immunosuppressant, MPA, Mycophenolate, Mycophenolic acid
Units: 
mg/L
Sample type and Volume required: 
4mL EDTA plasma.
Turnaround time: 
1 week
Contacts:
Immunosuppressant Service Laboratory at St Thomas'
020 7188 9652
St Thomas’ Hospital
North Wing - 4th Floor
Westminster Bridge Road
London SE1 7EH
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

Print as a PDF

Last updated: 03/11/2017