Thyroid (Anti-TPO) antibodies

Description: 
The immunoassay assay used by the laboratory tests for highly purified thyroid peroxidase (TPO) antigens. 75% - 90% of patients with Hashimoto’s thyroiditis have anti-TPO antibodies. The autoantibody is also present in 75% of patients with Graves’ disease and some 60% with postpartum thyroiditis. Anti-TPO may also be found in sub-clinical hypothyroidism (normal free T4 and elevated TSH) and autoimmune endocrinopathy.
Related condition or disease: 
Hashimoto's thyroiditis, papillary or follicular thyroid cancer
Reference range: 

TPO

negative 0 - 150

TG

negative 0 - 150

Units: 
U/ml
Department: 
Diagnostic Immunology and Allergy Department
Location: 
King's College Hospital
Sample type and Volume required: 
Clotted (Golt top vacutainer)
Turnaround time: 
2 days
Special sample instructions: 

All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.

Criteria for acceptance / rejections of sample
Storage and transport: 
Serum stored at 4°C should be sent by first class post
Time limit for extra tests: 
10 days
Contacts:
Diagnostic Immunology and Allergy Department at King's College Hospital
General Enquiry : 020 3299 8752 / 020 3299 1171
King's College Hospital
Bessemer Wing - 1st Floor
Denmark Hill
London SE5 9RS
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Diagnostic Immunology Laboratory at King's

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Last updated: 03/11/2021