The absolute number and percentage of different lymphocyte subsets can vary in various diseases. For example, in individuals with human immunodeficiency virus (HIV) infection, the number of CD4+ cells and the CD4+: CD8+ ratio is affected by the stage of disease and response to treatment. Thus, lymphocyte subset analysis can provide information regarding the immune status of the HIV infected patient and assist in monitoring therapy. Characteristic lymphocyte subset profile can be seen in a number of primary immunodeficiency disorders. A specific test request for T-cell subsets only test for CD4 and CD8 lymphocytes and is used for monitoring anti-retroviral treatment and HIV infection.
Lymphocytes CD 3 %, 55 - 83
Lymphocytes CD 3 absolute counts, 700 - 2100
Lymphycytes CD 4 %, 28 - 57
Lymphocytes CD 4 absolute counts, 300 - 1400
Lymphocytes CD 8 %, 10 - 39
Lymphocytes CD 8 absolute counts, 200 - 900
B cells CD19 %, 6 - 9
B cells absolute counts, 100 - 500
NK cells %, 7 - 31
NK cells absolute counts, 90 - 600
All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.
Bessemer Wing - 1st Floor
London SE5 9RS
Last updated: 03/11/2021