Hepatitis B surface Ab

Quantitative chemiluminescent immunoassay (CLIA) for the quantification of Hepatitis B surface antibodies in serum. Used to determine vaccine response and natural immunity. This assay is available as a screening or follow-up test Mon to Sun.
Clinical details: 
Used to determine vaccine response or natural immunity to Hepatitis B.
Reference range: 

Post primary vaccination course in immunocompetent individuals: >100 mIU/ml, further testing not needed, re-inforcing vaccine at 5yrs. >10 - <100mIU/ml, 1 further primary vaccine and re-inforcing vaccine at 5yrs, further testing not needed. <10mIU/ml, non-response to vaccine course, check for markers of current infection. Repeat vaccination course and testing 4 months post 2nd complete course. Individuals with levels of <10 mIU/ml post-vaccination requires Hepatitis B immunoglobulin if exposed to Hepatitis B.

milli-International Units/ml (mIU/ml)
Sample type and Volume required: 
2.5 – 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum). Note: If using Electronic Patient Record (EPR) please order "Hepatitis B surface Ab-mIU/ml".
Turnaround time: 
3 working days
Storage and transport: 
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Infection Sciences Department at St Thomas' Hospital
020 7188 8008
St Thomas' Hospital
North Wing - 5th Floor
Westminster Bridge Road
London SE1 7EH
Core opening hours: Monday-Friday 0900-1730

For clinical advice or interpretation of results, please contact the laboratory in the first instance.

Print as a PDF

Last updated: 04/12/2017