(SLA) Soluble Liver Antigen blot (part of autoimmune liver blot panel)
Description:
Part of Liver immunoblot panel, includes M2, LKM, LC-1 and SLA antibodies.
Anti-soluble liver antigen (anti-SLA) is one of a number of autoantibodies associated with autoimmune hepatitis (AIH). However, it is not unique to AIH and has been described in 10% of patients with chronic hepatitis C virus infection. It is detected by immunoassay but not by IIF. The antigenic target is a 50 kD cytosolic protein.
Anti-soluble liver antigen (anti-SLA) is one of a number of autoantibodies associated with autoimmune hepatitis (AIH). However, it is not unique to AIH and has been described in 10% of patients with chronic hepatitis C virus infection. It is detected by immunoassay but not by IIF. The antigenic target is a 50 kD cytosolic protein.
Reference range:
Negative
Units:
Negative - equivocal - positive
Department:
Location:
Sample type and Volume required:
Clotted (Gold top vacutainer)
Turnaround time:
6 days
Special sample instructions:
All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.
Storage and transport:
Samples may be stored at 4°C prior to despatch. The use of first class letter post without the need for coolant is sufficient.
Time limit for extra tests:
10 days
Contacts:
Diagnostic Immunology and Allergy Department at King's College Hospital
General Enquiry : 020 3299 8752 / 020 3299 1171
King's College Hospital
Bessemer Wing - 1st Floor
Denmark Hill
London SE5 9RS
Bessemer Wing - 1st Floor
Denmark Hill
London SE5 9RS
Laboratory:
Last updated: 01/03/2019
