PEG-ADA is used as an enzyme replacement therapy for patients with ADA deficiency. Activity in plasma is measured as the conversion of adenosine to inosine.
Patients with adenosine deaminase (ADA) deficiency may be treated with an infusion of PEG-ADA. ADA activity in plasma, together with red cell dATP levels, are useful for monitoring efficacy of treatment.
Related condition or disease:
Enzyme replacement therapy for adenosine deaminase deficiency.