Vitamin D

Vitamin D measured by chemiluminescent assay on the Abbott Architect
Clinical details: 
Assessment of vitamin D status is relevant in disturbances of calcium homeostasis. As 25-hydroxy vitamin D (25-OH-D) has a relatively long half-life and is the most abundant form of vitamin D, it is most often measured to assess vitamin D status. Its measurement is indicated in cases of suspected vitamin D deficiency e.g. rickets (children), osteomalacia (adults), neonatal hypocalcaemia, nutritional osteodystrophy (especially in the elderly, institutionalised and Asian populations, malabsorption (e.g. in cystic fibrosis, primary biliary cirrhosis) and in patients on long-term anticonvulsant therapy (barbiturate and phenytoin combination therapy in particular). Cases of vitamin D toxicity are rare and almost always iatrogenic in nature. In renal failure conversion of 25-OH-D to 1,25-OH-D may be inadequate, in which case measurement of calcitriol may be required.
Reference range: 

10-42 μg/L Target >20 μg/L

Sample type and Volume required: 
Serum (100 µL) is required.
Turnaround time: 
One to two weeks.
Storage and transport: 
Stable at 4°C for up to three days. Send by overnight first class post.
Clinical Biochemistry - Blood Sciences at King's College Hospital
020 3299 4126
King's College Hospital
Bessemer Wing
Denmark Hill
London SE5 9RS
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 03/05/2016