Vitamin B2

Description: 
Whole-blood vitamin B2 (flavin adenine dinucleotide (FAD)) is measured by HPLC with fluorsence detection
Clinical details: 
The term ‘vitamin B2’ indicates three compounds with vitamin B2 activity found in nature; flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and riboflavin. Vitamin B2 can be found in most unprocessed foods and at high concentrations in yeast extract liver and kidney. Meat, milk eggs and wheat bran are important dietary sources of vitamin B2 in the general population.
Because of its wide distribution in foods, symptoms of vitamin B2 deficiency are hard to distinguish in malnourished individuals due to concomitant deficiencies in other micronutrients. Experimentally, signs of deficiency are lesions of the lips (cheilosis), angles of the mouth (angular stomatitis), a fissured and magenta coloured tongue (glossitis) and follicular keratosis of the nose and forehead. The eyes can also be effected, symptoms include corneal vascularisation and photophobia.
Reference range: 

174-471

Synonyms or keywords: 
Riboflavin; flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN)
Units: 
nmol/L
Sample type and Volume required: 
whole blood EDTA
Call in advance: 
No
Turnaround time: 
10 days
Special sample instructions: 

Protect specimens from light and store frozen at -20 degrees, transport on ice.

Storage and transport: 
Transport on ice
Contacts:
Nutristasis Unit at St Thomas'
0207188 6815 / 89543
St Thomas' Hospital
North Wing - 4th Floor
Westminster Bridge Road
London SE1 7EH

Laboratory opening times
Monday - Friday 09.00 - 17.00
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 09/03/2017