Fetal genetic material (DNA) is present in the circulation of a pregnant woman; a maternal blood sample can be analysed in order to determine if there are missing or extra chromosomes (aneuploidies) in her fetus.
Extra chromosomes are related to conditions in pregnancy such as trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome) or trisomy 13 (Patau syndrome).
DNA from a sample of the mother’s blood is tested using a technology called “massively parallel DNA sequencing” which gives the proportion of DNA for each chromosome. An algorithm (calculation) then looks to see if any of the tested chromosomes is over- or under- represented in the fetus.
A blood sample in a Streck tube must reach the lab within one day of being taken. Test as early as 10 weeks, no limitations in reference to patient ethnicity, BMI, twin pregnancies, ART, or egg donor cases.
Synonyms or keywords:
Pregnancy, Prenatal, Down syndrome, Edwards syndrome, Patau syndrome, non-invasive, verifi, trisomy 21.