Varicella-zoster virus (VZV), a member of the herpes virus family, is a double stranded DNA virus that causes chickenpox (varicella) and results in a latent infection. Reactivation of the latent virus may subsequently occur causing shingles (zoster) and a number of neurological syndromes. An early diagnosis of VZV replication in the central nervous system can be obtained by detecting virus-specific DNA sequences in the cerebrospinal fluid (CSF) with the polymerase chain reaction (PCR).
Vesicle fluid or swab in VTM or CSF can be assessed for VZV DNA
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