Urinary Ethyl glucuronide(ETG) and Urinary ethyl sulphate (ETS) by LCMS
Description:
Urinary Ethyl glucoronide (EtG) and urinary ethyl sulphate (ETS) measured by liquid chromatography tandem mass spectrometry (LC-MS/MS)
Clinical details:
Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are metabolites of ethanol and are measured to assess recent alcohol consumption. Research data suggests that EtG is detectable in urine for 72-90 hours (Wienmann et al., 2004). There have been far fewer studies carried out on EtS but work done by Hoiseth et al (2008) suggested that EtS is detectable in urine for at least 40 hours. Therefore, quantitation of urinary EtG and EtS can provide an objective measure of alcohol abstinence and can be used in the evaluation of liver transplant patients.
Reference range:
EtG: <200 μg/L, EtS: <100 μg/L
Units:
μg/L
Department:
Location:
Sample type and Volume required:
Urine
Turnaround time:
10 days
Storage and transport:
Due to the possibility of false positive and false negative EtG results it is advisable to transport and store samples at -20 ºC until analysis.
Contacts:
Reference Biochemistry Department at King's College Hospital
020 3299 4107
King's College Hospital
Denmark Hill
London SE5 9RS
Denmark Hill
London SE5 9RS
Metabolic Laboratory at King's College Hospital
020 3299 4128
King's College Hospital
Denmark Hill
London SE5 9RS
Denmark Hill
London SE5 9RS
Laboratory:
Last updated: 11/12/2020
