Therapeutic Drug Monitoring (TDM): aciclovir and ganciclovir

This test is referred to another lab outside our network
This does not affect where samples are sent and where your results are issued.
Description: 
Aciclovir and ganciclovir levels are common virology request for TDM. These samples are sent to Bristol.

Aciclocir TDM indications:
Requesters have found these assays to be of value in patients with renal failure and/or
on ECMO, in cases of suspected neurotoxicity, or suspected poor absorption and in
some patients receiving valaciclovir.

Ganciclovir TDM indications:
Indications
Requesters have found these assays to be of value in patients with renal failure and to
monitor oral absorption, particularly in patients receiving valganciclovir.
Clinical details: 
Please specify which of these levels are required
Sample type and Volume required: 
Sample required
Approx. 1-2 mL of separated serum (if sample size is a problem the minimum
acceptable is 100 µL).

Turnaround time: 
2 days
Special sample instructions: 

Timing of samples
We recommend a pre dose sample and a post dose sample, taken either 1h after the
end of iv administration or 2h after oral administration.

Contacts:
South London Specialist Virology Centre
Results: 02032996155 Medical Advice: 02032996298
King's College Hospital
Cheyne Wing, 2nd Floor (opposite Liver ITU)
Denmark Hill
London SE5 9RS

DX address: South London (PHL) Kings DX 6570200 Peckham 90SE
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 07/08/2015