Rh/ K phenotyping

Description: 
Besides the RhD (RH1) antigen, other important antigens of the Rh system (ISBT, number 004) are: C (RH2), E (RH3), c (RH4) and e (RH5). Appropriate antigen-positive red cells may stimulate antibody production in antigen C (RH2), c (RH4), E (RH3) and e (RH5) negative individuals. The determination of the Rh phenotypes can, therefore be important during pregnancy, for previously transfused patients and for patients with known irregular antibodies. Approximately 9% of the Caucasian population are K (KEL1, K, K1) positive. The K antigen is strongly immunogenic. Anti-K has been reported as the cause of hemolytic transfusion reactions, both immediate and delayed, and hemolytic disease of the newborn.
Reference range: 

N/A

Units: 
N/A
Sample type and Volume required: 
6ml K2EDTA
Call in advance: 
NO
Turnaround time: 
4 hours
Time limit for extra tests: 
1 day
Contacts:
Blood Transfusion Laboratory at King's
02032993240
kch-tr.btl@nhs.net
Bessemer Wing
King's College Hospital
Bessemer Wing
Denmark Hill
London SE5 9RS
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 14/01/2021