Respiratory Panel - Lower

Description: 
Qualitative molecular respiratory lower panel assay using a multiplex tandem polymerase chain reaction (PCR) for the investigation of patients with a significant respiratory illness, suspected to be of an infectious aetiology, not diagnosed through frontline tests. This panel includes molecular targets for the detection of Legionella pneumophila, Legionella longbeachae, Mycoplasma pneumoniae, Bordetella species, (including B. pertussis, as a single target), Chlamydophila pneumoniae, Chlamydophila psittaci, and Pneumocystis jiroveci. Interpretation of results is complex and discussion with the relevant infection team is recommended. If samples reach the laboratory by 9:00am Mon to Sun a result should be available the same day. During the winter season the frequency of testing is increased to reflect demand. The out of season turnaround time is 2 working days. Note: If using Electronic Patient Record (EPR) please order "Respiratory Panel - LOWER".
Clinical details: 
Respiratory tract infections can be caused by a wide range of pathogens which are rarely clinically distinguishable. Correct and early identification has important treatment and infection control implications. Further comprehensive information is available in specific GSTT infection control guidelines via the GTi website or by contacting the virology SpR on x83140 or Duty Consultant via the switchboard.
Reference range: 

Not applicable

Synonyms or keywords: 
Legionnaires, PCP, Pertussis
Units: 
Qualitative Test - Detected/Not Detected
Sample type and Volume required: 
Bronchoalveolar lavage (BAL), non-directed bronchoalveolar lavage (NBL), and induced sputum (IS) in a self sealed valved container with no additives. Expectorated sputum is not suitable. Note: If using Electronic Patient Record (EPR) please order "Respiratory Panel - LOWER".
Turnaround time: 
2 working days
Storage and transport: 
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). Samples should be sent to CSR promptly as the sensitivity of assays that detect RNA/DNA depend on sample quality/integrity. Please store samples in a refrigerator if there is a delay in sending samples to CSR. Do NOT send samples via the air chute system.
Contacts:
Infection Sciences Department at St Thomas' Hospital
020 7188 8008
St Thomas' Hospital
North Wing - 5th Floor
Westminster Bridge Road
London SE1 7EH
Core opening hours: Monday-Friday 0900-1730


For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 25/11/2017