Pyruvate Kinase Assay

PK deficiency is probably the most common single known cause of hereditary nonspherocytic haemolytic anaemia
Reference range: 

11.0 - 19.0 IU/g Hb

Sample type and Volume required: 
Minimum 1 ml EDTA blood. FBC and reticulocyte count must be performed and results sent with samples. If more than one enzyme assay is required then > 1.0 ml of blood will be required.
Turnaround time: 
10 working days.
Special sample instructions: 

Blood transfusion within the last four months will affect results. Any red cell transfusion given must be declared on the request form.

Raised reticulocyte levels and/or raised Wbc levels may affect assay.

Storage and transport: 
Samples can be sent first class post. Samples must be received in the laboratory within 3 days of collection. If there is a delay in sending store at 4°C and send a normal sample collected on the same day to act as a travel control.
Please contact Business Development for pricing enquiries
Time limit for extra tests: 
Depends on tests required. Contact laboratory for further details.
Red Cell Centre - Protein Laboratory
020 3299 2455
c/o Central Specimen Reception
Blood Sciences Laboratory
Ground Floor Bessemer Wing
King’s College Hospital
Denmark Hill
London SE5 9RS
Mon-Fri, 9.00am-5.30pm
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 08/01/2020