Paul Bunnell Test

Description: 
The Paul Bunnell test is used to screen for infectious mononucleosis (IM), which is seen most commonly in adolescents and young adults. IM is caused by the Epstein-Barr virus. This infects B-lymphocytes which subsequently produce a heterophile antibody which is identified through its reaction with the Paul Bunnell antigen and is detected by a latex agglutination method.
Clinical details: 
The Paul Bunnell test is not always positive in IM. For higher sensitivity please request an EBV IgM assay.
Reference range: 

n/a

Synonyms or keywords: 
IM, Monospot, Infectious Mononucleosis, Glandular Fever, Mono
Sample type and Volume required: 
Whole blood / Serum
Turnaround time: 
1 day
Storage and transport: 
EDTA/SST
Contacts:
Blood Sciences Department-Guy's And St Thomas' Hospital
Result Query: 020 7188 8008
St Thomas' Hospital
North Wing - 5th Floor
Westminster Bridge Road
London SE1 7EH
Contact: 020 7188 9247

Guy's Hospital
Southwark Wing - 4th Floor
Great Maze Pond
London SE1 9RT
Contact: 020 7188 4781
Haematology Laboratory at Guy's and St Thomas' Clinical Advisory Service
Routine hours: bleep 1358
Paediatrics Routine hours: bleep 1621

Out of hours, weekend and bank holidays: 17:00-9:00 bleep 0294
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 07/08/2015