Haemoglobinopathy Screen

The haemoglobinopathy screen by HPLC is used in conjuction with clinical details and results of the FBC to identify Haemoglobin variants and thalassaemias. All Hb variants detected are confirmed by a secondary method. This screen is commonly used in antenatal screening, pre-operative screening and to provide HbS% for transfused sickle cell patients.
Clinical details: 
Screen for haemoglobin variants and thalassaemias
Reference range: 


Synonyms or keywords: 
Sickle test, HbS%, Hb electrophoresis, haemoglobin electrophoresis, thalassaemia screen, SICK, HPLC, haemoglobinopathy, variant identification, sickle, antenatal screen
Sample type and Volume required: 
Whole Blood
Turnaround time: 
3 working days
Storage and transport: 
Special Haematology Department at Guy's and St Thomas' Hospital
St Thomas’ Hospital
5th Floor - North Wing
Westminster Bridge Road
London SE1 7EH
Telephone - 0207 188 8189

Guy’s Hospital
4th Floor - Southwark Wing
Great Maze Pond
London SE1 9RT
Telephone - 020 7188 3421

Red Cell Laboratory at Guy's and St Thomas' Clinical Advisory Service
Monday - Friday 09:00 - 17:00 (adult):
jo.howard@gstt.nhs.uk, rachel.kesse-adu@gstt.nhs.uk and Kate.Gardner1@gstt.nhs.uk
Monday - Friday 09:00 - 17:00 (paediatric): baba.inusa@gstt.nhs.uk and Samah.Babiker@gstt.nhs.uk
Red Cell Laboratory at Guy's and St Thomas' Technical Advisory Service
Monday - Friday 09:00 - 17:00
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 11/01/2021