Fractional excretion of uric acid: FJHN / gout / hereditary renal hypouricaemia

Description: 
The fractional excretion of uric acid collection is decreased in gout and familial juvenile hyperuricaemia, also known as autosomal dominant tubulointerstitial kidney disease (ADTKD).
Clinical details: 
The fractional excretion of uric acid (FEur) is decreased in under-excreting gout and autosomal dominant tubulointerstitial kidney disease. FEur may be dramatically increased in patients with hereditary renal hypouricaemia.
Related condition or disease: 
Gout, FJHN, autosomal dominant tubulointerstitial kidney disease, hereditary renal hypouricaemia.
Reference range: 

Please contact the laboratory to discuss

Units: 
24h urine collection
Department: 
Biochemical Sciences Department
Location: 
St Thomas' Hospital
Sample type and Volume required: 
EDTA (purple top) and Lithium heparin (green top), 24 h urine collected with thymol
Turnaround time: 
3 weeks
Criteria for acceptance / rejections of sample
Storage and transport: 
10ml aliquot of warmed ( sink of hot water, 30min), well mixed 24h urine, store in fridge or freezer, can thaw in 1st class post.
Contacts:
Purine Research Laboratory at St Thomas'
020 7188 1266
St Thomas’ Hospital
North Wing - 4th Floor
Westminster Bridge Road
London SE1 7EH
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Purine Research Laboratory at St Thomas'

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Last updated: 15/12/2015