Measured as part of a profile including anti-Etanercept antibodies.
This test is not currently included in the laboratory's UKAS scope of accreditation to ISO15189:2012.
Test interpretation requires full clinical information: drug dosage/frequency, previous exposure to other biologics, time of sampling, duration of therapy and clinical assessment. Therapeutic range for Etenercept is yet to be defined but literature review of studies using our kit suggests Etanercept concentrations >3.1 μg/mL at 3 months predict response at 6 months.
Collect blood into a serum separation (SST™) or plain tube, preferably shortly before drug administration (trough levels). Centrifuge sample at 3000 rpm for 10 minutes, aliquot serum or plasma and keep in fridge until transport. If transport is going to be delayed by > 5 days, freeze at -20°C and send by first class post at a later date.
St Thomas' Hospital
Westminster Bridge Road
London SE1 7EH
Last updated: 18/12/2020