Diabetes Autoantibodies (INS, GAD, IA2)

Autoantibodies to Glutamic Acid Decarboxylase (GAD), Islet Antigen 2 (IA2), and Zinc-Transporter 8 (ZnT8) are diagnostic and prognostic markers of Type I Diabetes Mellitus. These autoantibodies are tested for by enzyme-linked immunoassay and is only able to be requested as a complete panel.

For GAD antibodies for neurological investigations, please see separate heading.
Reference range: 

Glutamic acid decarboxylase antibodies, <5.0
IA2 antibodies, <7.5
Zinc Transporter 8 antibodies, <15.0

Sample type and Volume required: 
Clotted (Gold top vacutainer)
Turnaround time: 
Assay is performed monthly
Special sample instructions: 

All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.

Storage and transport: 
Serum stored at 4ºC should be sent by 1st class post as soon as possible
Time limit for extra tests: 
10 days
Diagnostic Immunology and Allergy Department at King's College Hospital
General Enquiry : 020 3299 8752 / 020 3299 1171
King's College Hospital
Bessemer Wing - 1st Floor
Denmark Hill
London SE5 9RS
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 18/05/2018