Beta-2 Microglobulin

Description: 
The measurement of beta-2 microglobulin is used as prognostic indicator in myeloma. Concentrations will also be raised in patients with renal dysfunction.
Clinical details: 
Beta-2 microglobulin is a low molecular weight protein (11-12 kDa) found on the surface of all human cells as a component polypeptide chain of the HLA antigen complex. It is found in most body fluids and can be measured in serum, CSF, saliva, joint fluids and urine. The protein is excreted through the renal glomerulus, the majority being reabsorbed in the proximal tubules.
Related condition or disease: 
Multiple Myeloma, Malignancy, Renal Transplant, Collagen Vascular Disorders.
Reference range: 

0.8 - 2.34 mg/L

Units: 
mg/L
Department: 
Biochemical Sciences Department
Location: 
St Thomas' Hospital
Sample type and Volume required: 
Clotted (yellow SST tube). Serum.
Turnaround time: 
3 days
Criteria for acceptance / rejections of sample
Contacts:
Reference Chemistry Laboratory at St Thomas'
020 7188 1264
4th floor, North Wing
St Thomas' Hospital
Westminster Bridge Road
London SE1 7EH
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Reference Chemistry Laboratory at St Thomas'

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Last updated: 22/08/2023