Apoliprotein B-100

Description: 
Serum Apo A-1 and Apo B concentrations are recognised as better indicators of atherosclerotic risk than cholesterol and triglycerides alone. Atherosclerotic patients are better distinguished from normal individuals by the finding of increased plasma Apo B or decreased plasma Apo A-1 than by a raised LDL and low HDL. The ratio of the Apo A-1 to Apo B may provide a better index of cardiovascular risk than the individual values.
Clinical details: 
Apo B is central to lipoprotein transport and is essential for the secretion of Triglyceride (TG) rich lipoproteins from the liver and gut.
Related condition or disease: 
Cardiovascular disease.
Reference range: 

Hypobetalipoproteinaemia occurs at ApoB < 0.4 g/L Cardiovascular Risk increases with ApoB > 0.8 g/L

Units: 
g/L
Department: 
Biochemical Sciences Department
Location: 
St Thomas' Hospital
Sample type and Volume required: 
Clotted (yellow SST tube). Serum.
Turnaround time: 
3 days
Special sample instructions: 

Seat the patient 5 minutes before sampling. Fasting sample preferred, but non-fasting acceptable. Patient should follow their normal diet for 3 weeks prior to sampling.

Criteria for acceptance / rejections of sample
Contacts:
Reference Chemistry Laboratory at St Thomas'
020 7188 1264
4th floor, North Wing
St Thomas' Hospital
Westminster Bridge Road
London SE1 7EH
For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Reference Chemistry Laboratory at St Thomas'

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Last updated: 07/08/2015