Streptococcal Serology

Description: 
This serologic test is for antibodies to DNase B and streptolysin O (ASOT). Clinical indications typically include the investigation of rheumatic fever and glomerulonephritis.

Clinical details: 
A rise in ASOT between acute and convalescent sera provides supportive evidence of recent streptococcal infection.
Related condition or disease: 
Rheumatic fever, glomerulonephritis
Reference range: 

Interpretation of ASOT titre depends upon patient demographics. Where diagnostic uncertainty persists, please discuss with an infection specialist

Synonyms or keywords: 
ASOT
Department: 
Infection Sciences Department
Location: 
St Thomas' Hospital
Sample type and Volume required: 
2.5 – 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum).
Turnaround time: 
8 days
Special sample instructions: 

Send both acute and convalescent samples.

Criteria for acceptance / rejections of sample
Storage and transport: 
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Contacts:
Infection Sciences Department at St Thomas' Hospital
020 7188 8008
St Thomas' Hospital
North Wing - 5th Floor
Westminster Bridge Road
London SE1 7EH
Core opening hours: Monday-Friday 0900-1730


For clinical advice or interpretation of results, please contact the laboratory in the first instance.
Laboratory: 
Virology Laboratory at St Thomas'

Print as a PDF

Last updated: 20/11/2017