Glutamic Acid Decarboxylase (GAD) Antibodies

The assay detects antibody to the 65kD isoform of GAD. This autoantibody is seen in both type 1 diabetes and stiff person syndrome. GAD 65 is a pancreatic beta cell antigen. This assay is also performed with ZnT8 and IA2 antibodies (see Diabetic Autoantibodies). These autoantibodies are tested for by enzyme-linked immunoassay and is only able to be requested as a complete panel.
Reference range: 

Glutamic acid decarboxylase antibodies, <5.0
IA2 antibodies, <7.5
Zinc Transporter 8 antibodies, <15.0

Sample type and Volume required: 
Clotted (Gold top vacutainer) 4 ml
Turnaround time: 
28 days
Special sample instructions: 

All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.

Storage and transport: 
Serum stored at 4ºC should be sent by 1st class post as soon as possible
Time limit for extra tests: 
10 days
Diagnostic Immunology and Allergy Department at King's College Hospital
General Enquiry : 020 3299 8752 / 020 3299 1171
King's College Hospital
Bessemer Wing - 1st Floor
Denmark Hill
London SE5 9RS
For clinical advice or interpretation of results, please contact the laboratory in the first instance.

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Last updated: 18/05/2018